Banan Akram Abualkasem
Supervisor Name: Dr. Shatha Abdul Wadood & Dr. Isam Noori Salman
Diabetic foot ulceration (DFU) is the commonest cause of severe limb ischemia in the world. In diabetes mellitus, anemia is frequently unrecognized, yet studies have shown that it is twice as common in diabetics compared with non diabetics. We aimed to assess the incidence of anemia and further classify the iron deficiency seen in a high-risk DFU patient group. Methods: Fifty five patients with type 2 diabetes mellitus (T2DM) who undergone diabetic foot complication were selected from National Diabetes Center /Al-Mustansiyria University and Al-Yarmook hospital in Baghdad city. Diabetic foot patients were sub- grouped into two groups: infection (group P2) and non-infection (group P1) according to Wagner classification and clinical examination (WBC, ESR). Anemia was defined as hemoglobin (Hb) levels <12 g/dL. Hemoglobin (Hb) and ESR clinical examination were done for all groups. Descriptive data were expressed as mean ± SD. Baseline and outcome variables were compared using an independent student’s t-test. To evaluate the association of ESR and Hb; Pearson correlation‖ was employed. A p value of less than 0.05 was used to express significant statistical difference. Results: ESR and Hb measured for patients group P1 (n=30) and patients group P2 (n=25) and expressed as mean ± SD. It was found that the mean values of ESR of group P2 were (76.64±34.943 mm/hr), and of group P1 were (20.83±10.293) with significant increase (p= <0.000). While Hb of group P2 (11.616±3.1394) showed significant decrease (p= <0.006) in comparison with that of group P1 (13.698±2.2890). Pearson correlation (r) revealed that ESR was negatively correlated with Hb(r= −0.421; p<0.05) in the DFU patients group. Conclusion: Anemia and iron deficiency are a common problem in patients with DFU. Identification of both the presence of anemia in DFU patients is necessary to assess the role of iron replacement and therapeutic strategies. Iron deficiency is a common problem in patients with DFU. With current clinical markers, it is incredibly difficult to determine causal relationships and further in-depth scientific study is required.