Ali Hafedh Abbas1*     Alice Krikor Melconian2              Ali Hussein Ad’hiah1

1- Tropical-Biological Researches Unit, College of Science, University of Baghdad

2- Biotechnology Department, College of Science, University of Baghdad

Email: ali_habbs@scbaghdad.edu.iq

Abstract

Systemic lupus erythematosus (SLE) is a type of autoimmune disorder, caused by autoantibodies before clinical manifestations appeared. The etiology of the disease is not welldefined, although infectious agents that are involved in inducing SLE in genetically predisposed individuals have been suggested. Accordingly, the present study aimed to determine anticytomegalovirus (CMV) antibodies (IgG and IgM) in two groups of SLE women patients. The first included patients with renal complications (nephritis) while the second group involved patients that have arthritis. In both groups of SLE, a significant (p ≤ 0.05) increased in the percentage of anti-CMV antibodies was observed compared to controls. These results may suggest that CMV is one of the etiological factors that are involved in the pathogenesis of the disease.